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Tribute® UV-IR
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Feature
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Ultra PurePep Pathway “Inside” The proprietary ultra PurePep™ Pathway is enhanced with a dedicated microfluidic matrix valve block pathway for each reaction vessel resulting in pure peptides. Nitrogen and vacuum move all fluids through the system, the membranes are resistant to harsh chemicals, there is zero dead volumes, no cross-contamination, and best-in-class performance that lasts for years. Other systems use off-the-shelf valves that leak or corrode, result in cross-contamination, and quickly fail when exposed to harsh peptide synthesis chemicals. With the ultra PurePep Pathway inside the Tribute®instrument, all fluid deliveries are verified via optical sensors and you have reliable peptide purity every time. Infrared (IR) heating Efficient heating, reaching set temperature in minimal time. It is also fully-compatible with vortex mixing, so you can be sure you have an even temperature profile. Other heating systems use nitrogen mixing, which may result in hot and cold spots and effect the consistency of your chemistry. Real-Time UV monitoring Minimize trial-and-error when synthesizing difficult peptides using the Intellisynth® real-time UV monitoring on the Tribute instrument. What makes our UV monitoring different? Other systems just monitor the waste stream. We monitor your reaction solution while it’s mixing – that’s why we’re the only ones who can control the deprotection reaction times, not just the number of repetitions. Real-time UV monitoring ensures that reactions are completed efficiently and no excess reagent is wasted. Software features
Automated cleavage Tribute can deliver TFA to the reaction vessel from a solvent bottle or an amino acid vial. Afterwards, your cleaved peptide is collected in a 50 mL centrifuge vial in Tribute´s convenient collection stand. Just add either directly to the collection vial and centrifuge to precipitate your peptide! Automated cycle dependent volume incrementation Tribute can automatically adjust delivery volumes to account for resin volume increases as your synthesis progresses. Delivery volumes will increase by an increment of your choice each cycle. |
Specification |
Number of reaction vessels
Synthesis scale range Reaction vessel volume Number of solvent positions/sizes Number of amino acid positions Chemistries supported Activation Throughput Fluid measurement technique Fluid transfer method Agitation method Waste container Control interface Reporting Power Dimensions Weight Warranty Optional |
2 and no resin loader required
0.005 - 2.0 mmol (up to 2.1 g of resin per reaction vessel) Plastic, disposable: 10 mL, 45 mL Borosilicate glass: 10 mL, 40 mL 5 pressurized solvents (1 to 4 L each) 101 position amino acid rack, barcode scanning of amino acid vials Fmoc, t-Boc, organic, peptoid, combinatorial, branched, PNA In situ or pre-activation with HBTU, HATU, HCTU, TBTU, PyBOP, PyOxim, DIC/OxymaPure, DIC/HOBt, DIC/Oxyma-B and others User defined Fixed loop measurement with optical sensors Nitrogen or Argon pressure. Top down or bottom-up deliveries Nitrogen bubbling and vortex mixing - adjustable One 20 L container with over-flow sensor Proprietary Tribute control software, internal CPU, full-color chemical-resistant touchscreen Real-time log of each instrument function, print to file or printer 115 V/60 Hz or 230 V/50 Hz 43” x 25.4" x 23.2” (109 cm x 64 cm x 59 cm) Approximately 100 lbs. (45 kg) One year, parts and labor. Automated cleavage (Optional, Fmoc only, Cat#: TPS-CLV-OPT) Infrared (IR) Heating (Cat#: TPS-IR-OPT) Intellisynth Real-time UV Monitoring and feedback control system and software (Cat#: TPS-UV-OPT) E-mail-Text Message Status Reporting (Cat#: TPS-TXT-EML-RPT) User Workstation Utility |